• Users Online: 57
  • Print this page
  • Email this page
ORIGINAL ARTICLE
Year : 2021  |  Volume : 4  |  Issue : 2  |  Page : 59-63

Phenotypes of high-density lipoprotein cholesterol and their relationship with glycemic status in type 2 diabetic patients


1 Division of Endocrinology and Diabetes, Al Isawiya General Hospital, Ministry of Health, Directorate of Gurayat, Kingdom of Saudi Arabia
2 Public Health Specialist, Department of Community Medicine, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Anambra, Nigeria
3 Consultant Cardiologist, Department of Medicine, Cedarcrest Hospitals, Gudu, Abuja, Nigeria
4 Professor of Medicine and Consultant Endocrinologist, College of Medicine, University of Lagos, Lagos, Nigeria

Correspondence Address:
Dr. Chikezie Hart Onwukwe
Division of Endocrinology and Diabetes, Al Isawiya General Hospital, Ministry of Health, Directorate of Gurayat
Kingdom of Saudi Arabia
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jdep.jdep_4_21

Get Permissions

Background: There are varying reports on the association of high-density lipoprotein cholesterol (HDL-C) phenotypes and glycemia in type 2 diabetes mellitus (T2D) patients. Such information is lacking in Nigerian data. Aim: The aim of this study was to determine the relationship between HDL-C phenotypes and glycemic control in T2D patients. Materials and Methods: Clinical and laboratory data were collected from consenting T2D patients. Information was managed and analyzed with appropriate software. Results: Four hundred T2D patients consisting of 235 and 165 persons with and without poor glycemic control, respectively, were recruited for this study. There was a significant negative correlation between glycosylated hemoglobin (HbA1c) and the HDL2-C phenotype (rs = −0.12, P = 0.01). The correlation between HbA1c and the HDL3-C phenotype was not statistically significant (rs = −0.06, P = 0.21). Conclusion: The HDL2 phenotype has a stronger correlation with glycemic status than the HDL3 phenotype in T2D patients.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed942    
    Printed32    
    Emailed0    
    PDF Downloaded77    
    Comments [Add]    

Recommend this journal